PED: a novel predictor-encoder-decoder model for Alzheimer drug molecular generation

PED: a novel predictor-encoder-decoder model for Alzheimer drug molecular generation

Alzheimer's disease (AD) is a gradually advancing neurodegenerative disorder characterized by a concealed onset. Acetylcholinesterase (AChE) is an efficient hydrolase that catalyzes the hydrolysis of acetylcholine (ACh), which regulates the concentration of ACh at synapses and then terminates A...

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Bibliographic Details
Main Authors: Dayan Liu, Tao Song, Kang Na, Shudong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Artificial Intelligence
Subjects:
molecular generation
Alzheimer
deep learning
neural networks
drug design
Online Access:https://www.frontiersin.org/articles/10.3389/frai.2024.1374148/full

Internet

https://www.frontiersin.org/articles/10.3389/frai.2024.1374148/full

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