Phenomic Microglia Diversity as a Druggable Target in the Hippocampus in Neurodegenerative Diseases

Phenomic Microglia Diversity as a Druggable Target in the Hippocampus in Neurodegenerative Diseases

Phenomics, the complexity of microglia phenotypes and their related functions compels the continuous study of microglia in disease animal models to find druggable targets for neurodegenerative disorders. Activation of microglia was long considered detrimental for neuron survival, but more recently i...

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Bibliographic Details
Main Authors: Daniele Lana, Giada Magni, Elisa Landucci, Gary L. Wenk, Domenico Edoardo Pellegrini-Giampietro, Maria Grazia Giovannini
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Molecular Sciences
Subjects:
inflammaging
LPS inflammation
Alzheimer’s disease
ischemia
microbiota
α7nACh receptor
Online Access:https://www.mdpi.com/1422-0067/24/18/13668

Internet

https://www.mdpi.com/1422-0067/24/18/13668

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