Spatial analysis of the glioblastoma proteome reveals specific molecular signatures and markers of survival

Characterisation of molecular heterogeneity in glioblastoma would improve patient stratification. Here, the authors integrate spatial proteomics and clinical data from glioblastoma patients and identify 3 molecular groups and a 5-protein signature that was associated with survival.

Bibliographic Details
Main Authors: Marie Duhamel, Lauranne Drelich, Maxence Wisztorski, Soulaimane Aboulouard, Jean-Pascal Gimeno, Nina Ogrinc, Patrick Devos, Tristan Cardon, Michael Weller, Fabienne Escande, Fahed Zairi, Claude-Alain Maurage, Émilie Le Rhun, Isabelle Fournier, Michel Salzet
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34208-6