Arachidonic Acid Cascade and Eicosanoid Production Are Elevated While LTC4 Synthase Modulates the Lipidomics Profile in the Brain of the HIVgp120-Transgenic Mouse Model of NeuroHIV

Background: Combination antiretroviral therapy (cART) has transformed HIV infection from a terminal disease to a manageable chronic health condition, extending patients’ life expectancy to that of the general population. However, the incidence of HIV-associated neurocognitive disorders (HANDs) has p...

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Bibliographic Details
Main Authors: Nina Y. Yuan, Ricky Maung, Ziying Xu, Xianlin Han, Marcus Kaul
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/13/2123