Nucleocapsid protein-specific monoclonal antibodies protect mice against Crimean-Congo hemorrhagic fever virus

Nucleocapsid protein-specific monoclonal antibodies protect mice against Crimean-Congo hemorrhagic fever virus

Abstract Crimean-Congo hemorrhagic fever virus (CCHFV) is a WHO priority pathogen. Antibody-based medical countermeasures offer an important strategy to mitigate severe disease caused by CCHFV. Most efforts have focused on targeting the viral glycoproteins. However, glycoproteins are poorly conserve...

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Bibliographic Details
Main Authors: Aura R. Garrison, Vanessa Moresco, Xiankun Zeng, Curtis R. Cline, Michael D. Ward, Keersten M. Ricks, Scott P. Olschner, Lisa H. Cazares, Elif Karaaslan, Collin J. Fitzpatrick, Éric Bergeron, Scott D. Pegan, Joseph W. Golden
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46110-4

Internet

https://doi.org/10.1038/s41467-024-46110-4

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