The extant immunoglobulin superfamily, member 1 gene results from an ancestral gene duplication in eutherian mammals

The extant immunoglobulin superfamily, member 1 gene results from an ancestral gene duplication in eutherian mammals

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Immunoglobulin superfamily, member 1 (IGSF1) is a transmembrane glycoprotein with high expression in the mammalian pituitary gland. Mutations in the IGSF1 gene cause congenital central hypothyroidism in humans. The IGSF1 protein is co-translationally cleaved into N- and C-terminal domains (NTD and C...

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Bibliografiska uppgifter
Huvudupphovsmän: Courtney L. Smith, Paul M. Harrison, Daniel J. Bernard
Materialtyp: Artikel
Språk:English
Publicerad: Public Library of Science (PLoS) 2022-01-01
Serie:PLoS ONE
Länkar:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162367/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162367/?tool=EBI

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