The extant immunoglobulin superfamily, member 1 gene results from an ancestral gene duplication in eutherian mammals
Immunoglobulin superfamily, member 1 (IGSF1) is a transmembrane glycoprotein with high expression in the mammalian pituitary gland. Mutations in the IGSF1 gene cause congenital central hypothyroidism in humans. The IGSF1 protein is co-translationally cleaved into N- and C-terminal domains (NTD and C...
| المؤلفون الرئيسيون: | , , |
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| التنسيق: | مقال |
| اللغة: | English |
| منشور في: |
Public Library of Science (PLoS)
2022-01-01
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| سلاسل: | PLoS ONE |
| الوصول للمادة أونلاين: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162367/?tool=EBI |