COVID-19 induces more pronounced extracellular matrix deposition than other causes of ARDS

Abstract Background Lung fibrosis is a major concern in severe COVID-19 patients undergoing mechanical ventilation (MV). Lung fibrosis frequency in post-COVID syndrome is highly variable and even if the risk is proportionally small, many patients could be affected. However, there is still no data on...

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Main Authors: Natália de Souza Xavier Costa, Gabriel Ribeiro Júnior, Ellen Caroline Toledo do Nascimento, Jôse Mara de Brito, Leila Antonangelo, Caroline Silvério Faria, Jhonatas Sirino Monteiro, João Carlos Setubal, João Renato Rebello Pinho, Roberta Verciano Pereira, Marilia Seelaender, Gabriela Salim de Castro, Joanna D. C. C. Lima, Renata Aparecida de Almeida Monteiro, Amaro Nunes Duarte-Neto, Paulo Hilário Nascimento Saldiva, Luiz Fernando Ferraz da Silva, Marisa Dolhnikoff, Thais Mauad
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Respiratory Research
Subjects:
Online Access:https://doi.org/10.1186/s12931-023-02555-7