Empagliflozin Preserves Skeletal Muscle Function in a HFpEF Rat Model

Empagliflozin Preserves Skeletal Muscle Function in a HFpEF Rat Model

Besides structural alterations in the myocardium, heart failure with preserved ejection fraction (HFpEF) is also associated with molecular and physiological alterations of the peripheral skeletal muscles (SKM) contributing to exercise intolerance often seen in HFpEF patients. Recently, the use of So...

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Bibliographic Details
Main Authors: Ephraim B. Winzer, Antje Schauer, Erik Langner, Antje Augstein, Keita Goto, Anita Männel, Peggy Barthel, Anett Jannasch, Siegfried Labeit, Norman Mangner, Axel Linke, Volker Adams
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
HFpEF
ZSF1
SGLT2 inhibitor
MuRF1
skeletal muscle dysfunction
muscle atrophy
Online Access:https://www.mdpi.com/1422-0067/23/19/10989

Internet

https://www.mdpi.com/1422-0067/23/19/10989

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