Synthesis and Biological Evaluation of 2H-Indazole Derivatives: Towards Antimicrobial and Anti-Inflammatory Dual Agents

Synthesis and Biological Evaluation of 2H-Indazole Derivatives: Towards Antimicrobial and Anti-Inflammatory Dual Agents

Indazole is considered a very important scaffold in medicinal chemistry. It is commonly found in compounds with diverse biological activities, e.g., antimicrobial and anti-inflammatory agents. Considering that infectious diseases are associated to an inflammatory response, we designed a set of 2H-in...

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Bibliographic Details
Main Authors: Jaime Pérez-Villanueva, Lilián Yépez-Mulia, Ignacio González-Sánchez, Juan Francisco Palacios-Espinosa, Olivia Soria-Arteche, Teresita del Rosario Sainz-Espuñes, Marco A. Cerbón, Karen Rodríguez-Villar, Ana Karina Rodríguez-Vicente, Miguel Cortés-Gines, Zeltzin Custodio-Galván, Dante B. Estrada-Castro
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Molecules
Subjects:
anticandidal
indazole
Entamoeba histolytica
Giardia intestinalis
rational drug design
Trichomonas vaginalis
Online Access:https://www.mdpi.com/1420-3049/22/11/1864

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https://www.mdpi.com/1420-3049/22/11/1864

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