Formononetin Protects LPS-Induced Mastitis Through Suppressing Inflammation and Enhancing Blood-Milk Barrier Integrity via AhR-Induced Src Inactivation

Formononetin Protects LPS-Induced Mastitis Through Suppressing Inflammation and Enhancing Blood-Milk Barrier Integrity via AhR-Induced Src Inactivation

Formononetin (FOR), a natural flavonoid derived from Radix Astragali, has been reported to have anti-inflammatory and anti-oxidative effects. However, its protective mechanism against mastitis is still unknown. Nuclear factor kappa-B (NF-κB) signaling pathway plays an important role in inflammation,...

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Bibliographic Details
Main Authors: Kaihe Xiang, Peng Shen, Ziyang Gao, Zhuoyu Liu, Xiaoyu Hu, Bin Liu, Yunhe Fu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Subjects:
formononetin
LPS
mastitis
AhR
NF-κB
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.814319/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.814319/full

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