Formononetin Protects LPS-Induced Mastitis Through Suppressing Inflammation and Enhancing Blood-Milk Barrier Integrity via AhR-Induced Src Inactivation
Formononetin (FOR), a natural flavonoid derived from Radix Astragali, has been reported to have anti-inflammatory and anti-oxidative effects. However, its protective mechanism against mastitis is still unknown. Nuclear factor kappa-B (NF-κB) signaling pathway plays an important role in inflammation,...
Main Authors: | Kaihe Xiang, Peng Shen, Ziyang Gao, Zhuoyu Liu, Xiaoyu Hu, Bin Liu, Yunhe Fu |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-02-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2022.814319/full |
Similar Items
-
Epigenetic Regulations of AhR in the Aspect of Immunomodulation
by: Anna Wajda, et al.
Published: (2020-09-01) -
New Treatments in Renal Cancer: The AhR Ligands
by: Boris Itkin, et al.
Published: (2020-05-01) -
Effect of diet and intestinal AhR expression on fecal microbiome and metabolomic profiles
by: Fang Yang, et al.
Published: (2020-11-01) -
The Gut Microbiota Activates AhR Through the Tryptophan Metabolite Kyn to Mediate Renal Cell Carcinoma Metastasis
by: Guoyu Dai, et al.
Published: (2021-08-01) -
The Landscape of AhR Regulators and Coregulators to Fine-Tune AhR Functions
by: Marco Gargaro, et al.
Published: (2021-01-01)