KIF3A tail domain phosphorylation is not required for ciliogenesis in mouse embryonic fibroblasts

Summary: Primary cilia are essential signaling organelles that protrude from most cells in the body. Heterodimeric kinesin-2 (KIF3A/KIF3B/KAP3) powers several intracellular transport processes, including intraflagellar transport (IFT), essential for ciliogenesis. A long-standing question is how a mo...

Full description

Bibliographic Details
Main Authors: Ayoola S. Fasawe, Jessica M. Adams, Martin F. Engelke
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224003705