Nucleus accumbens core acetylcholine receptors modulate the balance of flexible and inflexible cue-directed motivation

Abstract Sign-tracking is a conditioned response where animals interact with reward-predictive cues due to the cues having motivational value, or incentive salience. The nucleus accumbens core (NAc) has been implicated in mediating the sign-tracking response. Additionally, acetylcholine (ACh) transm...

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Bibliographic Details
Main Authors: Erica S. Townsend, Kenneth A. Amaya, Elizabeth B. Smedley, Kyle S. Smith
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-40439-4