Identification of key genes in invasive clinically non-functioning pituitary adenoma by integrating analysis of DNA methylation and mRNA expression profiles

Abstract Background Tumor surrounding the internal carotid artery or invading to the cavernous sinus is an important characteristic of invasive pituitary adenoma, and a pivotal factor of tumor residue and regrowth. Without specific changes in serum hormone related to the adenohypophyseal cell of ori...

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Bibliographic Details
Main Authors: Sen Cheng, Weiyan Xie, Yazhou Miao, Jing Guo, Jichao Wang, Chuzhong Li, Yazhuo Zhang
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-019-02148-3