Pervasive Platelet Secretion Defects in Patients with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

Critically ill COVID-19 patients suffer from thromboembolic as well as bleeding events. Endothelial dysfunction, spiking of von Willebrand factor (vWF), and excessive cytokine signaling result in coagulopathy associated with substantial activation of plasmatic clotting factors. Thrombocytopenia seco...

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Bibliographic Details
Main Authors: Johannes Kalbhenn, Jan-Steffen Pooth, Georg Trummer, David Kranzhöfer, Axel Schlagenhauf, Barbara Zieger
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/1/193