Downregulation of Talin-1 expression associates with increased proliferation and migration of vascular smooth muscle cells in aortic dissection

Downregulation of Talin-1 expression associates with increased proliferation and migration of vascular smooth muscle cells in aortic dissection

Abstract Background This study aimed to assessed whether Talin-1 is involved in the pathogenesis of aortic dissection via regulating vascular smooth muscle cell (VSMC) biological function. Methods Human aortic samples were obtained from organ donors who died from nonvascular diseases as normal contr...

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Bibliographic Details
Main Authors: Xiaolong Wei, Yudong Sun, Yani Wu, Jiang Zhu, Bin Gao, Han Yan, Zhiqing Zhao, Jian Zhou, Zaiping Jing
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Cardiovascular Disorders
Subjects:
Talin-1
Aortic dissection
Vascular smooth muscle cell
Proliferation
Migration
Online Access:http://link.springer.com/article/10.1186/s12872-017-0588-0

Internet

http://link.springer.com/article/10.1186/s12872-017-0588-0

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