Gene Expression Profiling Elucidates Cellular Responses to NCX4040 in Human Ovarian Tumor Cells: Implications in the Mechanisms of Action of NCX4040

Gene Expression Profiling Elucidates Cellular Responses to NCX4040 in Human Ovarian Tumor Cells: Implications in the Mechanisms of Action of NCX4040

The nitric oxide donor, NCX4040 is a non-steroidal anti-inflammatory-NO donor and has been shown to be extremely cytotoxic to a number of human tumors, including ovarian tumors cells. We have found that NCX4040 is cytotoxic against both OVCAR-8 and its adriamycin-selected OVCAR-8 variant (NCI/ADR-RE...

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Bibliographic Details
Main Authors: Birandra K. Sinha, Erik J. Tokar, Jianying Li, Pierre R. Bushel
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cancers
Subjects:
microarray
gene expression
nitric oxide
TNFα
NCX4040
ROS
Online Access:https://www.mdpi.com/2072-6694/15/1/285

Internet

https://www.mdpi.com/2072-6694/15/1/285

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