Evolution of DC-SIGN use revealed by fitness studies of R5 HIV-1 variants emerging during AIDS progression

Evolution of DC-SIGN use revealed by fitness studies of R5 HIV-1 variants emerging during AIDS progression

<p>Abstract</p> <p>Background</p> <p>At early stages of infection CCR5 is the predominant HIV-1 coreceptor, but in approximately 50% of those infected CXCR4-using viruses emerge with disease progression. This coreceptor switch is correlated with an accelerated progressi...

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Bibliographic Details
Main Authors: Karlsson Anders, Purcell Damian FJ, Churchill Melissa J, Sterjovski Jasminka, Kuylenstierna Carlotta, Repits Johanna, Borggren Marie, Albert Jan, Gorry Paul R, Jansson Marianne
Format: Article
Language:English
Published: BMC 2008-03-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/5/1/28

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http://www.retrovirology.com/content/5/1/28

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