Regenerating human epithelia with cultured stem cells: feeder cells, organoids and beyond

Abstract More than 40 years ago, Howard Green's laboratory developed a method for long‐term expansion of primary human epidermal keratinocytes by co‐culture with 3T3 mouse embryonic fibroblasts. This was a breakthrough for in vitro cultivation of cells from human skin and later for other epithe...

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Bibliographic Details
Main Authors: Robert E Hynds, Paola Bonfanti, Sam M Janes
Format: Article
Language:English
Published: Springer Nature 2018-02-01
Series:EMBO Molecular Medicine
Subjects:
Online Access:https://doi.org/10.15252/emmm.201708213