Localization and Absolute Quantification of Dopamine in Discrete Intravesicular Compartments Using NanoSIMS Imaging

Localization and Absolute Quantification of Dopamine in Discrete Intravesicular Compartments Using NanoSIMS Imaging

The absolute concentration and the compartmentalization of analytes in cells and organelles are crucial parameters in the development of drugs and drug delivery systems, as well as in the fundamental understanding of many cellular processes. Nanoscale secondary ion mass spectrometry (NanoSIMS) imagi...

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Bibliographic Details
Main Authors: Stefania Rabasco, Tho D. K. Nguyen, Chaoyi Gu, Michael E. Kurczy, Nhu T. N. Phan, Andrew G. Ewing
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
NanoSIMS
dense core vesicles
vesicular compartmentalization
dopamine
absolute quantification
Online Access:https://www.mdpi.com/1422-0067/23/1/160

Internet

https://www.mdpi.com/1422-0067/23/1/160

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