Comparison of RNAscope and immunohistochemistry for evaluation of the UPK2 status in urothelial carcinoma tissues

Abstract Background UPK2 exhibits excellent specificity for urothelial carcinoma (UC). UPK2 evaluation can be useful in making the correct diagnosis of UC. However, UPK2 detection by immunohistochemistry (IHC) has relatively low sensitivity. This paper aimed to compare the diagnostic sensitivity of...

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Bibliographic Details
Main Authors: Jiangli Lu, Ming Zhao, Chenyan Wu, Chengbiao Chu, Chris Zhiyi Zhang, Yun Cao
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Diagnostic Pathology
Subjects:
Online Access:https://doi.org/10.1186/s13000-022-01191-x