Applications and Advances of Multicellular Tumor Spheroids: Challenges in Their Development and Analysis

Biomedical research requires both in vitro and in vivo studies in order to explore disease processes or drug interactions. Foundational investigations have been performed at the cellular level using two-dimensional cultures as the gold-standard method since the early 20th century. However, three-dim...

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Bibliographic Details
Main Authors: Achilleas G. Mitrakas, Avgi Tsolou, Stylianos Didaskalou, Lito Karkaletsou, Christos Efstathiou, Evgenios Eftalitsidis, Konstantinos Marmanis, Maria Koffa
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/8/6949