Structure-function analysis of the DNA-binding domain of a transmembrane transcriptional activator

Abstract The transmembrane DNA-binding protein CadC of E. coli, a representative of the ToxR-like receptor family, combines input and effector domains for signal sensing and transcriptional activation, respectively, in a single protein, thus representing one of the simplest signalling systems. At ac...

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Bibliographic Details
Main Authors: Andreas Schlundt, Sophie Buchner, Robert Janowski, Thomas Heydenreich, Ralf Heermann, Jürgen Lassak, Arie Geerlof, Ralf Stehle, Dierk Niessing, Kirsten Jung, Michael Sattler
Format: Article
Language:English
Published: Nature Portfolio 2017-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01031-9