Long non-coding RNAs LINC00689 inhibits the apoptosis of human nucleus pulposus cells via miR-3127-5p/ATG7 axis-mediated autophagy

This study aimed to explore the effects of long non-coding RNAs LINC00689 (LINC00689) in human nucleus pulposus cells (NPCs). NPCs were isolated and their morphology was observed. The proliferation and apoptosis of NPCs, and the levels of LINC00689, miR-3127-5p, Bax, Bcl-2, Cleaved caspase-3, ATG5,...

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Bibliographic Details
Main Authors: Wang Changsheng, Chen Rongsheng, Zhu Xitian, Zhang Xiaobo
Format: Article
Language:English
Published: De Gruyter 2022-11-01
Series:Open Medicine
Subjects:
Online Access:https://doi.org/10.1515/med-2022-0544