Characterization of a novel species-specific 51-amino acid peptide, PEP51, as a caspase-3/7 activator in ovarian follicles of the ascidian, Ciona intestinalis Type A

Characterization of a novel species-specific 51-amino acid peptide, PEP51, as a caspase-3/7 activator in ovarian follicles of the ascidian, Ciona intestinalis Type A

Invertebrates lack hypothalamic-pituitary-gonadal axis, and have acquired species-specific regulatory systems for ovarian follicle development. Ascidians are marine invertebrates that are the phylogenetically closest living relatives to vertebrates, and we have thus far substantiated the molecular m...

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Bibliographic Details
Main Authors: Tsubasa Sakai, Tatsuya Yamamoto, Takehiro Watanabe, Akiko Hozumi, Akira Shiraishi, Tomohiro Osugi, Shin Matsubara, Tsuyoshi Kawada, Yasunori Sasakura, Toshio Takahashi, Honoo Satake
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Endocrinology
Subjects:
test cells
ovarian peptides
apoptosis
ascidian
follicle
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1260600/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2023.1260600/full

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