Characterization of Novel <i>CYP2D6</i> Alleles across Sub-Saharan African Populations

Characterization of Novel <i>CYP2D6</i> Alleles across Sub-Saharan African Populations

The <i>CYP2D6</i> gene has been widely studied to characterize variants and/or star alleles, which account for a significant portion of variability in drug responses observed within and between populations. However, African populations remain under-represented in these studies. The incre...

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Bibliographic Details
Main Authors: Wendy Y. Wang, David Twesigomwe, Charity Nofziger, Amy J. Turner, Lena-Sophie Helmecke, Ulrich Broeckel, Ashley D. Derezinski, Scott Hazelhurst, Andrea Gaedigk
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Journal of Personalized Medicine
Subjects:
personalized medicine
pharmacogenetics
pharmacogenomics
CYP2D6
African ancestry
novel alleles
Online Access:https://www.mdpi.com/2075-4426/12/10/1575

Internet

https://www.mdpi.com/2075-4426/12/10/1575

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