Sustained Shugoshin 1 downregulation reduces tumor growth and metastasis in a mouse xenograft tumor model of triple-negative breast cancer
Abstract Background Triple-negative breast cancer (TBNC) is an aggressive breast cancer subtype with a poor prognosis. Shugoshin-1 (SGO1) protects chromatids from early separation. Previous studies from our group have demonstrated that transient SGO1 downregulation suppresses early stages of metasta...
Κύριοι συγγραφείς: | , , , , , , , , |
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Μορφή: | Άρθρο |
Γλώσσα: | English |
Έκδοση: |
BMC
2023-04-01
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Σειρά: | Cell Division |
Θέματα: | |
Διαθέσιμο Online: | https://doi.org/10.1186/s13008-023-00088-5 |