An updated mutation spectrum of the γ-secretase complex: Novel NCSTN gene mutation in an Indian family with hidradenitis suppurativa and acne conglobata

An updated mutation spectrum of the γ-secretase complex: Novel NCSTN gene mutation in an Indian family with hidradenitis suppurativa and acne conglobata

Background: Hidradenitis suppurativa (HS) is a complex, chronic inflammatory skin disorder whose pathophysiology is poorly understood. Genetic studies have shown that HS is predisposed by mutations in the γ-secretase gene, but only a proportion of familial and partial sporadic cases have been shown...

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Bibliographic Details
Main Authors: Uppala Ratnamala, Nayan K Jain, Devendrasinh D Jhala, Pullabatla V S. Prasad, Nazia Saiyed, Sreelatha Nair, Uppala Radhakrishna
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Indian Journal of Dermatology
Subjects:
chronic skin disorders
genetic heterogeneity
hidradenitis suppurativa
ncstn gene mutation
Online Access:http://www.e-ijd.org/article.asp?issn=0019-5154;year=2023;volume=68;issue=2;spage=141;epage=147;aulast=Ratnamala

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http://www.e-ijd.org/article.asp?issn=0019-5154;year=2023;volume=68;issue=2;spage=141;epage=147;aulast=Ratnamala

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