High production MBL2 polymorphisms protect against COVID-19 complications in critically ill patients: A retrospective cohort study

High production MBL2 polymorphisms protect against COVID-19 complications in critically ill patients: A retrospective cohort study

Mannose-binding lectin (MBL) binds to SARS-CoV-2, inhibits infection of susceptible cells, and activates the complement system via the lectin pathway. In this study, we investigated the association of MBL2 polymorphisms with the risk of hospitalization and clinical worsening in patients with COVID-1...

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Bibliographic Details
Main Authors: Lorena Viana de Andrade, Mirela Vanessa de Souza Sá, Beatriz Vasconcelos, Luydson Richardson Silva Vasconcelos, Ricardo Khouri, Carlos Dornels Freire de Souza, Anderson da Costa Armstrong, Rodrigo Feliciano do Carmo
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Heliyon
Subjects:
Innate immunity
Complement system
Mannose-binding lectin
Mannan-binding lectin
Polymorphism
SARS-CoV-2
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023108784

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http://www.sciencedirect.com/science/article/pii/S2405844023108784

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