Deficiency of ribosomal protein S26, which is mutated in a subset of patients with Diamond Blackfan anemia, impairs erythroid differentiation

Deficiency of ribosomal protein S26, which is mutated in a subset of patients with Diamond Blackfan anemia, impairs erythroid differentiation

Introduction: Diamond Blackfan anemia (DBA) is a rare congenital disease characterized by defective maturation of the erythroid progenitors in the bone marrow, for which treatment involves steroids, chronic transfusions, or hematopoietic stem cells transplantation. Diamond Blackfan anemia is caused...

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Bibliographic Details
Main Authors: Noemy Piantanida, Marta La Vecchia, Marika Sculco, Maria Talmon, Gioele Palattella, Ryo Kurita, Yukio Nakamura, Antonella Ellena Ronchi, Irma Dianzani, Steven R. Ellis, Luigia Grazia Fresu, Anna Aspesi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Genetics
Subjects:
ribosomal protein
Diamond Blackfan anemia
ribosomopathy
RPS26
erythroid differentiation
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.1045236/full

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https://www.frontiersin.org/articles/10.3389/fgene.2022.1045236/full

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