The potential of sheep in preclinical models for bone infection research – A systematic review

Background: Reliable animal models are critical for preclinical research and should closely mimic the disease. With respect to route of infection, pathogenic agent, disease progression, clinical signs, and histopathological changes. Sheep have similar bone micro- and macrostructure as well as compar...

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Bibliographic Details
Main Authors: Michael L.C. Beagan, Chris H. Dreyer, Louise K. Jensen, Henrik E. Jensen, Thomas E. Andersen, Soeren Overgaard, Ming Ding
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Journal of Orthopaedic Translation
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X24000159