Systematic transcriptome profiling of pyroptosis related signature for predicting prognosis and immune landscape in lower grade glioma

Systematic transcriptome profiling of pyroptosis related signature for predicting prognosis and immune landscape in lower grade glioma

Abstract Background Pyroptosis is a programmed cell death mediated by the gasdermin superfamily, accompanied by inflammatory and immune responses. Exogenously activated pyroptosis is still not well characterized in the tumor microenvironment. Furthermore, whether pyroptosis-related genes (PRGs) in l...

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Bibliographic Details
Main Authors: Huihan Yu, Meiting Gong, Jian Qi, Chenggang Zhao, Wanxiang Niu, Suling Sun, Shuyang Li, Bo Hong, Junchao Qian, Hongzhi Wang, Xueran Chen, Zhiyou Fang
Format: Article
Language:English
Published: BMC 2022-08-01
Series:BMC Cancer
Subjects:
Pyroptosis
Lower-grade glioma
Prognostic signature
Tumor immune microenvironment
Drug screening
Fedratinib
Online Access:https://doi.org/10.1186/s12885-022-09982-7

Internet

https://doi.org/10.1186/s12885-022-09982-7

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