Patient-Derived, Drug-Resistant Colon Cancer Cells Evade Chemotherapeutic Drug Effects via the Induction of Epithelial-Mesenchymal Transition-Mediated Angiogenesis

Patient-Derived, Drug-Resistant Colon Cancer Cells Evade Chemotherapeutic Drug Effects via the Induction of Epithelial-Mesenchymal Transition-Mediated Angiogenesis

Cancer cells can exhibit resistance to different anticancer drugs by acquiring enhanced anti-apoptotic potential, improved DNA injury resistance, diminished enzymatic inactivation, and enhanced permeability, allowing for cell survival. However, the genetic mechanisms for these effects are unknown. T...

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Bibliographic Details
Main Authors: Jin Hong Lim, Kyung Hwa Choi, Soo Young Kim, Cheong Soo Park, Seok-Mo Kim, Ki Cheong Park
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
patient-derived colon cancer
drug resistance
oxaliplatin
lenvatinib
angiogenesis
Online Access:https://www.mdpi.com/1422-0067/21/20/7469

Internet

https://www.mdpi.com/1422-0067/21/20/7469

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