Physiology of Highly Radioresistant Escherichia coli After Experimental Evolution for 100 Cycles of Selection

Physiology of Highly Radioresistant Escherichia coli After Experimental Evolution for 100 Cycles of Selection

Ionizing radiation (IR) is lethal to most organisms at high doses, damaging every cellular macromolecule via induction of reactive oxygen species (ROS). Utilizing experimental evolution and continuing previous work, we have generated the most IR-resistant Escherichia coli populations developed to da...

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Bibliographic Details
Main Authors: Steven T. Bruckbauer, Joel Martin, Benjamin B. Minkoff, Mike T. Veling, Illissa Lancaster, Jessica Liu, Joseph D. Trimarco, Brian Bushnell, Anna Lipzen, Elizabeth A. Wood, Michael R. Sussman, Christa Pennacchio, Michael M. Cox
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Microbiology
Subjects:
ionizing radiation
experimental evolution
reactive oxygen species
double-strand breaks
DNA repair
Escherichia coli
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.582590/full

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https://www.frontiersin.org/article/10.3389/fmicb.2020.582590/full

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