P151 Microvascular Dysfunction is Associated with Impaired Beta-cell Function: The Maastricht Study

Abstract Background The pathophysiological mechanism underlying beta-cell dysfunction in type 2 diabetes (T2D) is not fully understood. Recent animal studies suggest that microvascular dysfunction (MVD) may lead to insufficient delivery of oxygen and nutrients to beta-cells as well as an attenuated...

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Main Authors: Wenjie Li, Alfons Houben, Tos Berendschot, Carroll Webers, Abraham Kroon, Marleen van Greevenbroek, Carla van der Kallen, Ronald Henry, Simone Sep, Pieter Dagnelie, Nicolaas Schaper, Simone Eussen, Casper Schalkwijk, Miranda Schram, Coen Stehouwer
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Artery Research
Online Access:https://doi.org/10.2991/artres.k-191224.171