Mast cells and tryptase are linked to itch and disease severity in mycosis fungoides: Results of a pilot study

Mast cells and tryptase are linked to itch and disease severity in mycosis fungoides: Results of a pilot study

IntroductionIn mycosis fungoides (MF), the most common cutaneous T-cell lymphoma, itch is a frequent clinical symptom. Whether mast cells (MCs), eosinophils (Eos) or their mediators play a role in MF-associated itch or disease severity is controversially discussed. Here, we explored the role of MC a...

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Bibliographic Details
Main Authors: Dorothea Terhorst-Molawi, Katharina Lohse, Katharina Ginter, Viktoria Puhl, Martin Metz, Man Hu, Marcus Maurer, Sabine Altrichter
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
mycosis fungoides
cutaneous T-cell lymphoma
mast cell
eosinophil
tryptase
itch (pruritus)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.930979/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.930979/full

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