Identification of a Variant in <i>APOB</i> Gene as a Major Cause of Hypobetalipoproteinemia in Lebanese Families

Identification of a Variant in <i>APOB</i> Gene as a Major Cause of Hypobetalipoproteinemia in Lebanese Families

Familial hypobetalipoproteinemia (FHBL) is a codominant genetic disorder characterized by reduced plasma levels of low-density lipoprotein cholesterol and apolipoprotein B. To our knowledge, no study on FHBL in Lebanon and the Middle East region has been reported. Therefore, we conducted genetic stu...

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Bibliographic Details
Main Authors: Carine Ayoub, Yara Azar, Yara Abou-Khalil, Youmna Ghaleb, Sandy Elbitar, Georges Halaby, Selim Jambart, Marie-Hélène Gannagé-Yared, Cesar Yaghi, Carole Saade Riachy, Ralph El Khoury, Jean-Pierre Rabès, Mathilde Varret, Catherine Boileau, Petra El Khoury, Marianne Abifadel
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Metabolites
Subjects:
familial hypobetalipoproteinemia
low-density lipoprotein cholesterol
<i>APOB</i> gene
PCSK9
non-alcoholic fatty liver
diabetes
Online Access:https://www.mdpi.com/2218-1989/11/9/564

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https://www.mdpi.com/2218-1989/11/9/564

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