PepT1-targeted nanodrug based on co-assembly of anti-inflammatory peptide and immunosuppressant for combined treatment of acute and chronic DSS-induced ColitiS

PepT1-targeted nanodrug based on co-assembly of anti-inflammatory peptide and immunosuppressant for combined treatment of acute and chronic DSS-induced ColitiS

IntroductionInflammatory bowel disease (IBD), as a chronic and recurrent inflammatory bowel diseases with limited therapeutic outcomes, is characterized by immune disorders and intestinal barrier dysfunction. Currently, the most medications used to cure IBD in clinic just temporarily induce and main...

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Bibliographic Details
Main Authors: Daifang Zhang, Longqi Jiang, Fengxu Yu, Pijun Yan, Yong Liu, Ya Wu, Xi Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-08-01
Series:Frontiers in Pharmacology
Subjects:
colitis
PepT1-targeting
combined treatment
KPV
FK506
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1442876/full

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https://www.frontiersin.org/articles/10.3389/fphar.2024.1442876/full

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