Benzylidene Barbituric Acid Derivatives Shown Anticonvulsant Activity on Pentylenetetrazole-Induced Seizures in Mice: Involvement of Nitric Oxide Pathway

Benzylidene Barbituric Acid Derivatives Shown Anticonvulsant Activity on Pentylenetetrazole-Induced Seizures in Mice: Involvement of Nitric Oxide Pathway

ABSTRACT Background: Barbituric acid derivatives have long been used as central nervous system (CNS) suppressants, such as sedatives, hypnotics and anticonvulsants. In addition, previous studies have implicated the involvement of nitric oxide (NO) in the anticonvulsive effects of barbiturates in CN...

Повний опис

Бібліографічні деталі
Автори: Shabnam Mahernia, Niusha Sharifi, Malihe Hassanzadeh, Nastaran Rahimi, Nastaran Pourshadi, Arash Amanlou, Ahmad Reza Dehpour, Massoud Amanlou
Формат: Стаття
Мова:English
Опубліковано: Tabriz University of Medical Sciences 2018-12-01
Серія:Pharmaceutical Sciences
Предмети:
Barbituric acid
Nitric oxide
Nitric oxide synthase inhibitors
Pentylenetetrazole
Seizure
Mice
Онлайн доступ:https://ps.tbzmed.ac.ir/PDF/PHARM_3497_20180619145232

Інтернет

https://ps.tbzmed.ac.ir/PDF/PHARM_3497_20180619145232

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