Identification of a chemoresistance-related prognostic gene signature by comprehensive analysis and experimental validation in pancreatic cancer

Identification of a chemoresistance-related prognostic gene signature by comprehensive analysis and experimental validation in pancreatic cancer

BackgroundChemoresistance is a major hurdle to improving the prognosis of pancreatic cancer (PC). This study aimed to identify key genes regulating chemoresistance and develop a chemoresistance-related gene signature for prognosis prediction.MethodsA total of 30 PC cell lines were subtyped according...

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Bibliographic Details
Main Authors: Junliang Chen, Zhihao Liu, Zhiyuan Wu, Wenjun Li, Xiaodong Tan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Oncology
Subjects:
pancreatic cancer
chemoresistance
gemcitabine
prognosis
immunotherapy
tumor microenvironment
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1132424/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1132424/full

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