Network pharmacology and molecular docking analysis on Shenfu Qiangxin indicate mTOR is a potential target to treat heart failure

Network pharmacology and molecular docking analysis on Shenfu Qiangxin indicate mTOR is a potential target to treat heart failure

Abstract Background Heart failure (HF) is one of the major causes of mortality worldwide with high recurrence rate and poor prognosis. Our study aimed to investigate potential mechanisms and drug targets of Shenfu Qiangxin (SFQX), a cardiotonic-diuretic traditional Chinese medicine, in treating HF....

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Bibliographic Details
Main Authors: Peilin Zou, Jiajun Li, Yucong Zhang, Zonghao Qian, Hao Nie, Ni Yang, Le Zhang, Li Lin, Dewei Peng, Cuntai Zhang
Format: Article
Language:English
Published: BMC 2024-03-01
Series:European Journal of Medical Research
Subjects:
Shenfu Qiangxin
Heart failure
mTOR
Molecular docking
Network pharmacology
Online Access:https://doi.org/10.1186/s40001-024-01732-8

Internet

https://doi.org/10.1186/s40001-024-01732-8

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