CEACAMs interaction with Helicobacter pylori HopQ supports the type 4 secretion system-dependent activation of non-canonical NF-κB

CEACAMs interaction with Helicobacter pylori HopQ supports the type 4 secretion system-dependent activation of non-canonical NF-κB

Helicobacter pylori infection represents a major risk factor for the development of gastric diseases and gastric cancer. The capability of H. pylori to inject the virulence factor cytotoxin-associated gene A (CagA) depends on a type IV secretion system (T4SS) encoded by the cag pathogenicity island...

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Bibliographic Details
Main Authors: Gunter Maubach, Olga Sokolova, Christian Täger, Michael Naumann
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:International Journal of Medical Microbiology
Subjects:
Cytotoxin-associated gene A (CagA)
NF-κB-inducing kinase (NIK)
Outer membrane protein (OMP)
p100
RelA
RelB
Online Access:http://www.sciencedirect.com/science/article/pii/S1438422120300540

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http://www.sciencedirect.com/science/article/pii/S1438422120300540

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