Comprehensive Landscape of BRAF Variant Classes, Clonalities, and Co-Mutations in Metastatic Colorectal Cancer Using ctDNA Profiling

Comprehensive Landscape of BRAF Variant Classes, Clonalities, and Co-Mutations in Metastatic Colorectal Cancer Using ctDNA Profiling

Although V600E accounts for the majority of the <i>BRAF</i> mutations in metastatic colorectal cancer (mCRC), non-V600 <i>BRAF</i> variants have been shown in recent years to represent a distinct molecular subtype. This study provides a comprehensive profile of <i>BRAF&...

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Bibliographic Details
Main Authors: Benny Johnson, Van Morris, Xuemei Wang, Arvind Dasari, Kanwal Raghav, John Paul Shen, Michael S. Lee, Ryan Huey, Christine Parseghian, Jason Willis, Robert Wolff, Leylah M. Drusbosky, Michael J. Overman, Scott Kopetz
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cancers
Subjects:
atypical <i>BRAF</i>
metastatic colorectal cancer
<i>BRAF</i> mutation
<i>KRAS</i> mutation
<i>NRAS</i> mutation
Online Access:https://www.mdpi.com/2072-6694/16/4/737

Internet

https://www.mdpi.com/2072-6694/16/4/737

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