Molecular Anatomy of the EML4-ALK Fusion Protein for the Development of Novel Anticancer Drugs

The <i>EML4</i> (echinoderm microtubule-associated protein-like 4)-<i>ALK</i> (anaplastic lymphoma kinase) fusion gene in non-small-cell lung cancer (NSCLC) was first identified in 2007. As the EML4-ALK fusion protein promotes carcinogenesis in lung cells, much attention has...

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Bibliographic Details
Main Authors: So Yeong Cheon, Sunghark Kwon
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/6/5821