Molecular Anatomy of the EML4-ALK Fusion Protein for the Development of Novel Anticancer Drugs
The <i>EML4</i> (echinoderm microtubule-associated protein-like 4)-<i>ALK</i> (anaplastic lymphoma kinase) fusion gene in non-small-cell lung cancer (NSCLC) was first identified in 2007. As the EML4-ALK fusion protein promotes carcinogenesis in lung cells, much attention has...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-03-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/24/6/5821 |