Pulmonary hypertension alters blood flow distribution and impairs the hyperemic response in the rat diaphragm

Pulmonary hypertension alters blood flow distribution and impairs the hyperemic response in the rat diaphragm

Pulmonary hypertension (PH) is characterized by pulmonary vascular remodeling, respiratory muscle and cardiac impairments, and exercise intolerance. Specifically, impaired gas exchange increases work of the diaphragm; however, compromised contractile function precludes the diaphragm from meeting the...

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Bibliographic Details
Main Authors: Kiana M. Schulze, Andrew G. Horn, Ramona E. Weber, Bradley J. Behnke, David C. Poole, Timothy I. Musch
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Physiology
Subjects:
perfusion
oxygen transport
vascular dysfunction
monocrotaline
respiratory muscle
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1281715/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2023.1281715/full

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