From Young to Old: Mimicking Neuronal Aging in Directly Converted Neurons from Young Donors

A substantial challenge in human brain aging is to find a suitable model to mimic neuronal aging in vitro as accurately as possible. Using directly converted neurons (iNs) from human fibroblasts is considered a promising tool in human aging since it retains the aging-associated mitochondrial donor s...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Nimmy Varghese, Amandine Grimm, M. Zameel Cader, Anne Eckert
Format: Artikel
Sprache:English
Veröffentlicht: MDPI AG 2024-07-01
Schriftenreihe:Cells
Schlagworte:
Online Zugang:https://www.mdpi.com/2073-4409/13/15/1260