Xenotransplantation of Human Spermatogonia Into Various Mouse Recipient Models

Spermatogonial stem cells are the foundation of continuous spermatogenesis in adult mammals. Xenograft models have been established to define human SSCs, mostly using infertile and immune-deficient mice as the recipients for human germ cell transplantation. However, it is time-consuming to prepare s...

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Bibliographic Details
Main Authors: Dongli Liang, Qi Sun, Zijue Zhu, Chuanyun Wang, Shicheng Ye, Zheng Li, Yuan Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.883314/full