Peripheral immune landscape for hypercytokinemia in myasthenic crisis utilizing single-cell transcriptomics

Peripheral immune landscape for hypercytokinemia in myasthenic crisis utilizing single-cell transcriptomics

Abstract Background Myasthenia gravis (MG) is the most prevalent autoimmune disorder affecting the neuromuscular junction. A rapid deterioration in respiratory muscle can lead to a myasthenic crisis (MC), which represents a life-threatening condition with high mortality in MG. Multiple CD4+ T subset...

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Bibliographic Details
Main Authors: Huahua Zhong, Xiao Huan, Rui Zhao, Manqiqige Su, Chong Yan, Jie Song, Jianying Xi, Chongbo Zhao, Feifei Luo, Sushan Luo
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Journal of Translational Medicine
Subjects:
Myasthenia gravis
Myasthenic crisis
Single-cell sequencing
Innate immunity
Monocyte
Online Access:https://doi.org/10.1186/s12967-023-04421-y

Internet

https://doi.org/10.1186/s12967-023-04421-y

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