Heterogeneity and stochastic growth regulation of biliary epithelial cells dictate dynamic epithelial tissue remodeling

Dynamic remodeling of the intrahepatic biliary epithelial tissue plays key roles in liver regeneration, yet the cellular basis for this process remains unclear. We took an unbiased approach based on in vivo clonal labeling and tracking of biliary epithelial cells in the three-dimensional landscape,...

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Bibliographic Details
Main Authors: Kenji Kamimoto, Kota Kaneko, Cindy Yuet-Yin Kok, Hajime Okada, Atsushi Miyajima, Tohru Itoh
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/15034